Earticle

초록

영어

This experiment was conducted to investigate the genetic effects of candidate genes on the growth of spleen and liver tissues using dietary Curcuma longa (C. longa) supplementation. Expression analyses of candidate genes regarding animal growth was performed in order to determine the factors affecting the growth related to immune components of Curucumin, Turmerone, and Zingiberene as the bile secretion Paratolyl methyl carbinol (PTMC). The animals were divided into four groups of five chicks supplied with experimental diets of C. longa at 0.25, 0.5 and 1% and controls. The 19 growth-related genes were known to cell maturation, differentiation significant expression patterns in this analysis. Expression of growth response-related genes in chicks supplemented with 1% of C. longa showed better growth performance than chicks with 0.25 and 0.5% in spleen (p<0.05). The IGF1, MSTN, POU1F1, ADCYAP1 gene were known to central roles in mediating gonadotropin function, regulating steroidogenesis and promoting oocyte growth and maturation. Sex steroids, androgen and estrogen can affect sex differentiation and also can affect muscle development. On the other hand, GHSR and FABP3 gene showed significant expression patterns in this analysis. The results would be used as basic information for the variation of growth-related genes expression on the cell growth, sex cell growth, and sex hormones according to dietary supplementation with C. longa in chickens.

목차

ABSTRACT
 INTRODUCTION
 MATERIALS AND METHODS
  Experimental Design
  Sample Collection
  Statistical Analysis
  RNA Extraction, Reverse Transcription, and Quantitative Real-Time PCR
 RESULTS AND DISCUSSION
 REFERENCES

키워드

저자

• Sun-Ae Park [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea ]
• Lee-Kyung Kim [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea, ]
• Chang-Min Park [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea ]
• Seung-Chang Kim [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea ]
• Seung-Hwan Lee [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea ]
• Ji-Woong Lee [ Devision of Animal Science, Insti. of Ag. Sci. and Tech., Chonnam National University, Chonnam 500-757, Republic of Korea ] Corresponding author
• Bong-Hwan Choi [ Division of Animal Genomics & Bioinformatics, National Institute of Animal Science, RDA, Suwon, 441-706, Republic of Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Reproductive & developmental biology

• 간기

  계간

• pISSN

  1738-2432

• eISSN

  2288-0151

• 수록기간

  1977~2018

• 십진분류

  KDC 527 DDC 636