To illustrate the different kinetics of cellular self-repair mechanism under external perturbations from outer environment, a mathematical model of DNA damage repair process is proposed by using the Kinetic Theory of Active Particles (KTAP) framework. The profile of cellular self-repair process is represented by two sub-populations, each of which is made up of the active particles with different discrete states. The dynamic kinetics of DNA damage generation, repair mRNA transcription, Repair Protein (RP) translation, DSBC synthesis are investigated by the particle interactions between the molecular pairs within DNA and RP sub-systems.
목차
Abstract 1. Introduction 2. Method 3. Result 3.1 DSBs Generation Induced by IR 3.2 Repair mRNA Transcription and RP Translation 3.3 DSBCs Synthesis Kinetics 3. Conclusion Acknowledgements References
키워드
IRKTAPCellular Self-RepairDNA DamageModeling.
저자
Jinpeng Qi [ College of Information Science & Technology, Donghua University ]
Yongsheng Ding [ College of Information Science & Technology, Donghua University ]
Tao Gong [ College of Information Science & Technology, Donghua University ]
Ying Lin [ Institute of Biological Sciences and Biotechnology, Donghua University ]
보안공학연구지원센터(IJHIT) [Science & Engineering Research Support Center, Republic of Korea(IJHIT)]
설립연도
2006
분야
공학>컴퓨터학
소개
1. 보안공학에 대한 각종 조사 및 연구
2. 보안공학에 대한 응용기술 연구 및 발표
3. 보안공학에 관한 각종 학술 발표회 및 전시회 개최
4. 보안공학 기술의 상호 협조 및 정보교환
5. 보안공학에 관한 표준화 사업 및 규격의 제정
6. 보안공학에 관한 산학연 협동의 증진
7. 국제적 학술 교류 및 기술 협력
8. 보안공학에 관한 논문지 발간
9. 기타 본 회 목적 달성에 필요한 사업
간행물
간행물명
International Journal of Hybrid Information Technology
간기
격월간
pISSN
1738-9968
수록기간
2008~2016
십진분류
KDC 505DDC 605
이 권호 내 다른 논문 / International Journal of Hybrid Information Technology Vol.5 No.2