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Segmentation and Removal of Interphase Cells from Chromosome Images using Multidirectional Block Ranking

첫 페이지 보기
  • 발행기관
    보안공학연구지원센터(IJBSBT) 바로가기
  • 간행물
    International Journal of Bio-Science and Bio-Technology SCOPUS 바로가기
  • 통권
    Vol.5 No.3 (2013.06)바로가기
  • 페이지
    pp.79-92
  • 저자
    Sivaramakrishnan Rajaraman, Ganesh Vaidyanathan, Arun Chokkalingam
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A207153

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원문정보

초록

영어
This paper proposes Multidirectional Block Ranking based segmentation and removal of Interphase cells from chromosome images. The efficiency of automatic karyotyping decreases with the presence of undivided, condensed mass of chromosomes called Interphase cells, stain, debris and other unwanted interferences in the chromosome image. The algorithm segments and removes these interferences and enhances the accuracy of automatic karyotyping. The method is tested and excellent segmentation accuracy is accomplished. The chromosome image is preprocessed and a boundary-mapping algorithm is applied to identify the Region of Interest (RoI). The image is divided into blocks and ranks are assigned to all the blocks using Gaussian Ranking Functions (GRF) based on their contribution to the RoI. A higher rank is assigned to the block contributing more while a lesser rank is assigned to other blocks that contribute less to the RoI. The Interphase cells that constitute the RoI are removed from the chromosome images based on the cumulative rank obtained by the blocks in the chromosome image. The proposed algorithm is applied to segment and remove Interphase cells, stains, dirt and other particles that exhibit structural homogeneity. The algorithm gives accurate results in applications where the RoI to be segmented share the grey level with the background wherein the traditional image segmentation methods fall short of accomplishing precise segmentation results.

목차

Abstract
 1. Introduction
 2. Materials and Methods
  2.1. Boundary mapping using Morphological Operators
 3. Multidirectional Block Ranking
 4. Feature Extraction
 5. Performance Evaluation
 6. Results and Discussions
 7. Future Enhancements
 Acknowledgements
 References

키워드

Interphase cells Automatic karyotyping Multidirectional block ranking Gaussian Ranking Function (GRF) Cumulative rank Structural homogeneity Region of Interest (RoI) Segmentation accuracy

저자

  • Sivaramakrishnan Rajaraman [ Department of Biomedical Engineering, Sri Sivasubramaniya Nadar College of Engineering ]
  • Ganesh Vaidyanathan [ Department of Electronics and Communication Engineering, Sri Venkateshwara College of Engineering ]
  • Arun Chokkalingam [ Department of Electronics and Communication Engineering, R.M.K. College of Engineering and Technology ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    보안공학연구지원센터(IJBSBT) [Science & Engineering Research Support Center, Republic of Korea(IJBSBT)]
  • 설립연도
    2006
  • 분야
    공학>컴퓨터학
  • 소개
    1. 보안공학에 대한 각종 조사 및 연구 2. 보안공학에 대한 응용기술 연구 및 발표 3. 보안공학에 관한 각종 학술 발표회 및 전시회 개최 4. 보안공학 기술의 상호 협조 및 정보교환 5. 보안공학에 관한 표준화 사업 및 규격의 제정 6. 보안공학에 관한 산학연 협동의 증진 7. 국제적 학술 교류 및 기술 협력 8. 보안공학에 관한 논문지 발간 9. 기타 본 회 목적 달성에 필요한 사업

간행물

  • 간행물명
    International Journal of Bio-Science and Bio-Technology
  • 간기
    격월간
  • pISSN
    2233-7849
  • 수록기간
    2009~2016
  • 등재여부
    SCOPUS
  • 십진분류
    KDC 505 DDC 605

이 권호 내 다른 논문 / International Journal of Bio-Science and Bio-Technology Vol.5 No.3

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