Earticle

초록

영어

This study investigated the anti-inflammatory effects of Xanthoceras sorbifolia of seeds oil on RAW264.7 macrophages and TPA (12-O-tetra decanoylphorbol-acetate)-induced ear edema mice. MTT assay method to measure cytotoxicity was formed in RAW264.7 cell. The anti-inflammatory effect was measured by ability to inhibit production nitric oxide (NO) in RAW264.7 cell. Hexane and eight-percent methanol fractions from Xanthoceras sorbifolia seeds oil did not show cytotoxicity. Hexane and eight-percent methanol fractions were showed significantly inhibitory effect on NO production. TPA-induced acute edema was developed in the mouse ears, and Xanthoceras sorbifolia seeds oil dissolved in acetone was applied to inflamed ears. It was found out that Xanthoceras sorbifolia seeds oil could significantly reduce th ear swelling, compared to the control. Overall results indicate that the Xanthoceras sorbifolia seeds oil has anti-inflammatory activity and could be used as a resource of anti-inflammatory materials.

목차

Abstract
 서론
 재료 및 방법
  실험재료
  종자유 추출
  문관나무 종자유의 정제
  문관나무 종자유 추출물의 제조
  세포독성 측정
  Nitric oxide 생성량 측정
  실험동물
  염증 유발 및 문관나무 종자유 처치
  귀 부종 측정
  통계처리
 결과
  세포독성 및 Nitric oxide 생성 저해 효과
  마우스 귀 부종 염증 억제 효과
 고찰
 결론
 감사의 글
 References

키워드

저자

• 정혜정 [ Hye Jeong Jeong | 강원도농업기술원 ]
• 이기연 [ Ki Yeon Lee | 강원도농업기술원 ]
• 홍수영 [ Soo Young Hong | 강원도농업기술원 ]
• 허남기 [ Nam Ki Heo | 강원도농업기술원 ]
• 김희연 [ Hee Yeon Kim | 강원도농업기술원 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Journal of Forest and Environmental Science [산림과학연구]

• 간기

  계간

• pISSN

  2288-9744

• eISSN

  2288-9752

• 수록기간

  1981~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 526 DDC 634