Earticle

초록

영어

Recently there has been considerable interest in trying to translate microtiter plate based assays into microfluidic platforms. Due to their small scale, microfluidic platforms have many practical advantages such as highly efficient reaction, sensitive detection and massive parallelism. Compared with microtiter plate based assays, the microfluidic platforms can continuously perform more complicated operation. Current method to mimic the microtiter plate based assay in microfluidic platforms categorized into droplet array. We present a programmable multiple droplet array systems that include droplet generation, array, storage, fusion, and elimination process. By integrating pneumatic microvalves with microfluidic system, we can achieve to precisely manipulate individual droplets for delivering, merging and mixing of distinct droplets. This method readily allow us to achieve in-situ monitoring and screening of several types of chemical and biochemical reactions. Thus, we expect that the proposed platform will be a powerful tool to study fundamental biological and chemical reactions, high throughput screening (HTS), or combinatorial synthesis or analysis.

키워드

저자

• Si Hyung JIN [ Dept. of Chemical engineering, Chungnam National University, Daejeon ]
• Heon-Ho JEONG [ Dept. of Chemical engineering, Chungnam National University, Daejeon ]
• Young moo NOH [ Dept. of Chemical engineering, Chungnam National University, Daejeon ]
• Chang-Soo LEE [ Dept. of Chemical engineering, Chungnam National University, Daejeon ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576