Earticle

초록

영어

Metabolic processes in biological systems can largely be classified into primary and secondary metabolisms. Notably, via secondary metabolism, a wide variety of metabolites with low-molecular weight can be synthesized, some with potent physiological activities. Fungi or microalgae are of particular interest due to their capacity to produce an extensive array of secondary metabolites, which have tremendous importance for humans with beneficial (e.g., antibiotics) or detrimental (e.g., mycotoxins) properties (Demain & Fang, 2000). In this study, we utilized functional genomics, forward and reverse genetics, proteomics, and high efficiency homologous recombination, to better understand the complex secondary metabolism regulations in fungi. By doing so, several fungal mutant strains with significantly altered secondary metabolites could be identified and these strains will have a high potential for subsequent biotechnological applications. In microalgae, our results reveal that MAP kinase signaling pathways are highly conserved, since MAP kinase pathways tested in several microalgal species are all negatively implicated in carotenoid biosynthesis. Currently, we are striving to develop the promising microalgal strains and these strains will be utilized in downstream process based on photobioreactors. Some current research efforts in our research group are also focused on developing the appropriate microalgal cultivation strategy using LED light.

키워드

저자

• Yoon-E CHOI [ LED Agri-bio Fusion Technology Research Center, Chonbuk National University. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576