The oligosaccharides (OS) in milk are known to play essential roles in the development of the infant. However, the carbohydrate composition of milk from different animal sources as well as human milk varies. Formulated infant milkpowder made from cow milk lacks certain bioactive carbohydrate structures and shows limited amounts of N-acetylneuraminic acid and fucose, compared to human milk. Our strategy to discover the difference of bioactive carbohydrate structures in milk and the potential for the development of novel functional dairy products is based on the analysis of glycosylation profiles of free and protein bound OS with a unique chromatography-based methodology. This approach is currently also adopted for a broader range of foodstuff, which shows carbohydrate related biological functions. Additionally, the level of nutritional components (e.g. lipids) has been found to influence many biological events. The effect of the nutritional level on glycan structures is also of great interest and to monitor the structural changes, and to reveal the underlying biochemical mechanisms is another target of our research.
저자
Josef Voglmeir [ Laboratory of Glycosciences, College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China ]
Li Liu [ Laboratory of Glycosciences, College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.