This experiment was carried out to prove the efficacy of Rhynchosia volubilis (RV) extract in ovariectomized rats. Forty rats were divided into 4 groups, administrated saline after sham operation(sham-op), saline after ovariectomy (control), RV 500 mg/kg after ovariectomy and 0.042 mg/kg Livial after ovariectomy (positive control). We examined the water extract of RV that is capable of affects osteoblast proliferation using MG-63 and HOS-TE85. Dual energy X-ray absorptiometry (DEXA) was used to measure the tibia bone mineral density of the ovariectomized rat and sham-op groups. Serum was collected for analysis of Ca and phosphorous. The results showed that body weight gain, Tibia BMD and BMC was significantly different among groups. These results suggest that RV has therapeutic effect on ovariectomized rats.
키워드
Rhynchosia VolubilisovariectomizedDEXABMDBMC
저자
Sang-Won Lee [ Department of Herbal Crop Research National Institute of Horticultural and Herbal Science, RDA ]
Hyung-Don Kim [ Department of Herbal Crop Research National Institute of Horticultural and Herbal Science, RDA ]
Young-Ock Kim [ Department of Herbal Crop Research National Institute of Horticultural and Herbal Science, RDA ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.