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Preparation of Medium-Molecular Weight Chitosan and Its Antimicrobial Activity Against Antibiotic –Resistance Microorganisms.

첫 페이지 보기
  • 발행기관
    한국당과학회 바로가기
  • 간행물
    한국당과학회 학술대회 바로가기
  • 통권
    4th 2009 Annual Meeting of Korean Society for Glycoscience in 2009 (2009.11)바로가기
  • 페이지
    pp.60-61
  • 저자
    Jae-Kweon Park, Hye-Ran Moon, Woo-Jung Kim, Sung-Min Kim, Yong Il Park
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A192550

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원문정보

초록

영어
Antimicrobial activities of a series of chitosans with different molecular weight were investigated against a Gram-positive meticillin-resistance Staphylococcus aureus (MRSA) and a Gram-negative bacteria Pseudomonas aeruginosa to determine the effects of molecular weight and concentration on the inhibition of bacterial growth. Medium-molecular weight chitosan (P6-MMC) with average of 110-kDa was obtained by enzymatic digestion of high molecular weight of native chitosan using an immobilized chitosanase (N-174) on silica-gel. In comparison with high molecular weight of native chitosan, low-molecular weight chitiosan (LMWC) and medium-molecular weight of chitosan (MMWC), P6-MMC prepared in this study has shown the most significant antimicrobial activities in a dose-dependent manner against MRSA, and toward P. aeruginosa as well. Our present data observed in this study suggest that antimicrobial activity against antibiotic-resistance microorganisms of a series of chitosan varied depending on the concentration of chitosan, molecular weight of chitosan, and type of microorganisms.

저자

  • Jae-Kweon Park [ Department of Biotechnology and Biomaterial Engineering Research Center, The Catholic University of Korea ]
  • Hye-Ran Moon [ Department of Biotechnology and Biomaterial Engineering Research Center, The Catholic University of Korea ]
  • Woo-Jung Kim [ Department of Biotechnology and Biomaterial Engineering Research Center, The Catholic University of Korea ]
  • Sung-Min Kim [ Department of Biotechnology and Biomaterial Engineering Research Center, The Catholic University of Korea ]
  • Yong Il Park [ Department of Biotechnology and Biomaterial Engineering Research Center, The Catholic University of Korea ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국당과학회 [Korean Society for Glycoscience]
  • 설립연도
    2006
  • 분야
    의약학>약학
  • 소개
    본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.

간행물

  • 간행물명
    한국당과학회 학술대회
  • 간기
    연간
  • 수록기간
    2006~2022
  • 십진분류
    KDC 517 DDC 614

이 권호 내 다른 논문 / 한국당과학회 학술대회 4th 2009 Annual Meeting of Korean Society for Glycoscience in 2009

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