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Functional Analysis of AtbZIP17 & 28 as Signaling Components of Unfolded Protein Response in Arabidopsis

첫 페이지 보기
  • 발행기관
    한국당과학회 바로가기
  • 간행물
    한국당과학회 학술대회 바로가기
  • 통권
    4th 2009 Annual Meeting of Korean Society for Glycoscience in 2009 (2009.11)바로가기
  • 페이지
    pp.53-53
  • 저자
    Jae Ho Cha, Jeong Chan Moon, Joo Mi Jeon, Wahyu Indra Fanata, Bo Hwa Son, In Jung Jung, Jae Yong Yoo, Je Hein Kim, Rikno Harmoko, Ki Seong Ko, Sang Yeol Lee, Kyun Oh Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A192541

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원문정보

초록

영어
In the endoplasmic reticulum (ER) elicit a highly conserved ER stress response called the unfolded protein response (UPR). Accumulation of misfolded proteins elicits signals by three types of ER stress sensor/transducer in mammal. Among them, ATF6 is a type II transmembrane protein normally retained in the ER. In this study, we have identified two membrane-associated basic domain/leucine zipper (bZIP) factors AtbZIP17 and AtbZIP28 in Arabidopsis thaliana as candidates for ER stress sensors/transducers similar to mammalian ATF6. AtbZIP17 and AtbZIP28 have N-terminal bZIP domain, a transmembrane segment, respectively. Truncated forms of AtbZIP17 and AtbZIP28 lacking the C-terminal domain were overexpressed in Arabidopsis. AtbZIP17 and AtbZIP28 overexpressed Arabidopsis showed upregulated the expression of ER chaperone genes in the absence of stress conditions. Interestingly, they growed bigger and more vigorously than WT in normal growth condition. Under stress conditions, AtbZIP17 and AtbZIP28 overexpression plants showed enhanced stress tolerance compare with that of WT plants. These results suggest that AtbZIP17 and AtbZIP28 function as sensor/transducer in Arabidopsis to mediate ER stress response related to UPR. [Supported by EB-NCRC & BK21 program]

저자

  • Jae Ho Cha [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Jeong Chan Moon [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Joo Mi Jeon [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Wahyu Indra Fanata [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Bo Hwa Son [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • In Jung Jung [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Jae Yong Yoo [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Je Hein Kim [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Rikno Harmoko [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Ki Seong Ko [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Sang Yeol Lee [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]
  • Kyun Oh Lee [ Division of Applied Life Science (BK21 Program), EB-NCRC and PMBBRC, Gyeongsang National University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국당과학회 [Korean Society for Glycoscience]
  • 설립연도
    2006
  • 분야
    의약학>약학
  • 소개
    본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.

간행물

  • 간행물명
    한국당과학회 학술대회
  • 간기
    연간
  • 수록기간
    2006~2022
  • 십진분류
    KDC 517 DDC 614

이 권호 내 다른 논문 / 한국당과학회 학술대회 4th 2009 Annual Meeting of Korean Society for Glycoscience in 2009

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