2008 Eastern Asian Glycoscience Symposium (2008.11)바로가기
페이지
pp.32-32
저자
Hisashi Narimatsu
언어
영어(ENG)
URL
https://www.earticle.net/Article/A192303
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원문정보
초록
영어
For these 7 years, we have been developing new technologies for Glycomics with the sponsorship of the New Energy and Industrial Technology Development Organization (NEDO). We discovered new glyco-genes and constructed human glyco-gene library consisting of 184 genes. Knowledge of the substrate specificities of these gene products allowed us to better understand the molecular basis of human glycosylation. Taking full advantage of our glyco-gene library, we developed a glycan library that was then used as standards to develop instruments for glycan structural analysis, such as mass spectrometer-based glycan sequencer and lectin microarray-based glycan profiler. Association of aberrant glycosylation with cancer has long been recognized. However, much of the discovery still depends on serendipity, and biological meanings of these cancer-related glycosylation patterns are only gradually uncovered. In 2006, we launched a new project termed Medical Glycomics (MG) project. Our aims in the project are two-folds: (1) development of discovery systems for cancer-related glyco -biomarkers, and (2) functional analysis of the cancer-associated glycosylation. We present many candidates for cancer-glyco-biomarker which would be useful for diagnosis.
저자
Hisashi Narimatsu [ Research Center for Medical Glycoscience (RCMG), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan. ]
본 학회는 화학, 생화학, 분자생물학, 미생물학, 식품공학, 의학, 약학, 유전공학 및 생물공학, 환경 및 기타 공업 등 전 분야의 탄수화물관련 이론과 기술을 연구 발전시키고 산학협동을 통해 이를 보급하여 국내 관련 산업의 발전 및 국민생활의 과학화에 기여하고자 하며, 이러한 목표와 비젼의 실현을 위해 회원들이 적극적인 참여와 활동을 전개하고자 한다.
간행물
간행물명
한국당과학회 학술대회
간기
연간
수록기간
2006~2022
십진분류
KDC 517DDC 614
이 권호 내 다른 논문 / 한국당과학회 학술대회 2008 Eastern Asian Glycoscience Symposium