Porous tricalcium phosphate beads(beta TCP) with a controllable pore size were fabricated using an emulsion templating method. An aqueous dispersion of TCP powders and gelatin as achieved using ball mill with Zirconia balls. Primary oil-in-water (O/W) emulsions with a different size in oil droplets were prepared by changing the homogenization speed, where toluene and the aqueous TCP phases were served as oil and water, respectively. The primary O/W emulsion was introduced into a fluidic device using cooled toluene as the continuous phase, evolving into oil-in-water-in-oil (O/W/O) emulsion droplets. The O/W/O emulsion droplets were freeze-dried and then calcined at various temperature, finally obtaining TCP beads with micro and macro pore sizes. These micro and macro porous beads have great potential for applications in bone tissue engineering.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
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