It is well established that cancer is death-causing factor in the world. H. fusiforme has potential as a new functional food component that evidences immunomodulatory activities and anticancer activity This study was conducted to investigate the effects of enzyme extracts Hizikia fusiforme (Viscozyme, Celluclast, Alcalase, Lysing enzyme, flavozyme, pectinex, Neutrase, AMG, Termamyl) on Human cancer cell (HCT-116(colorectal carcinoma:KCLB 10247), HeLa(cervix, uterine ademocarinoma: KCLB 10002), MKN-45(stomach adenocarcinoma: KCLB 30177). Enzyme extracts had on apoptosis of the cancer cell. we confirm the cell activity 0, 0.25, 0.5, 1 ㎍/ml extract of the H.fusiforme. Enzyme extract was treated at 50℃, 24 hr. We determined the cytotoxic effect of these fractions against human cancer cell lines using MTT assay. A s a result, the apoptosis of the human cancer cell lines (HCT-116, MKN-45, HeLa) were efficiency in the sample treated Viscozyme, Flavourzyme, Neutrase respectively.
키워드
ApoptosisHCT-116HeLaMKN-45
저자
Bo mi NAM [ Dept. of Chemical engineering, Chosun University, Gwangju, 501-759. ]
Jung-heon LEE [ Dept. of Chemical engineering, Chosun University, Gwangju, 501-759. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동