Earticle

초록

영어

The potentials of medicinal plants and their miraculous properties are used for the skin health since human civilization. Intrinsic or extrinsic factors involved in the skin aging process, proceeds through MMP-1 catalyzed collagen degradation. The collagen plays a structural and functional scaffold in the extracellular matrix of skin and other tissues. The aim of the present work to screen the plant extracts of Dendropanax, Cornus, and Lycium, to search the potential inhibitor of MMP-1 expression. These plants were highly cited for their medicinal properties like anti-aging, anti-inflammatory, anti-oxidant, and immunoregulatory, etc... We extracted the plant’s active parts by various extraction procedures. The antioxidant properties of the extract were evaluated by the DPPH assay. The effect of extract on the collagen synthesis and cell viability (MTT assay) was measured to compare the inhibition in MMP-1 expression and toxicity caused, respectively. The fraction showed desirable activity was further purified by HPLC. The primitive result shows the potentials of the plant’s active compound can use as the cosmetic ingredient for minimize the aging dependent wrinkle formation.

키워드

저자

• HyeRyeong LIM [ Dept. of Biological Engineering, Inha University, Incheon. ]
• Vivek KUMAR MORYA [ Dept. of Biological Engineering, Inha University, Incheon. ]
• Hyang-Bok LEE [ Dept. of Biological Engineering, Inha University, Incheon. ]
• Jungeun KIM [ Dept. of Biological Engineering, Inha University, Incheon. ]
• DaHoon YOON [ Dept. of Biological Engineering, Inha University, Incheon. ]
• Eun-Ki KIM [ Dept. of Biological Engineering, Inha University, Incheon. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576