Fluorescence polymers have received a great deal of interest due to their unique physical properties such as conductivity, electroluminescence. Moreover, polyphenylenevinylene (PPV) and their derivatives are currently the most popular class of conjugated polymers used in electronic materials, such as organic light-emitting diodes (OLEDs). Hybrid nanomaterials containing two or more functionalities have been received attention as attractive candidates for biomedical application. Furthermore, superparamagnetic iron oxide (Fe3O4) nanoparticles have been extensively studied for use as magnetic resonance imaging (MRI) contrast agents. In this study, we prepared multifunctional nanoparticles incorporating fluorescent polymer and Fe3O4 nanoparticles, and coated by ionic polymer layers. Properties of prepared multifunctional nanoparticles were characterized by transmission electron microscopy (TEM) and particle analyzer, UV spectrometer and PL spectrometer. The bioapplication of nanoparticles was evaluated by specific binding capability, cell permeability and viability by optical and MR imaging. Consequently, we expect that our nanoparticles will have considerable potential as a powerful novel material within the emerging field of biomedical, such as drug delivery, therapeutics and magnetic resonance imaging (MRI) contrast agents.
키워드
Fluorescentnanoparticlesbioapplication
저자
Hee Hyun JANG [ BioNanotechnology Reasearch Center, Korea Reasearch Institute of Bioscience and Biotechnology, Korea. ]
Chang Soo LEE [ BioNanotechnology Reasearch Center, Korea Reasearch Institute of Bioscience and Biotechnology, Korea. ]
Bong Hyun CHUNG [ BioNanotechnology Reasearch Center, Korea Reasearch Institute of Bioscience and Biotechnology, Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동