Earticle

초록

영어

Saururus chinensis is a traditional Korean herb for curing liver diseases. So this study was performed to investigate anti-inflammatory and anti-oxidative improving effects of Saururus chinensis fermented with Bacillus licheniformis sp. SMs-07 extract(SCFE) in the liver and sera of LPS-treated rats. SCFE, Saururus chinensis extract(SCE) and rutin were orally administered into experimental groups for 30 days, while the normal and control groups were administered with water. On day 31, rats were given 5 mg/kg of LPS(the normal group was given a vehicle). LPS-treated groups markedly increased the levels of AST and ALT in sera and MDA in the liver homogenates and mitochondrial fractions, but decreased the levels of SOD, CAT and GPx in liver homogenates and mitochondrial fractions. SCFE and SCE groups decreased AST, ALT and MDA, but they increased SOD, CAT and GPx. SCFE had better activities than SCE. It could be concluded that the fermentation played the important role in the improvement of anti-oxidation and anti-inflammation.

키워드

저자

• Bae Jin HA [ Department of Pharmaceutical Engineering, Silla University, Busan, 614-735. ]
• Ga Yeon CHAE [ Department of Pharmaceutical Engineering, Silla University, Busan, 614-735. ]
• Ryun Hee KWON [ Department of Pharmaceutical Engineering, Silla University, Busan, 614-735. ]
• Min Jeong KIM [ Department of Pharmaceutical Engineering, Silla University, Busan, 614-735. ]
• Min Woo JANG [ Department of Pharmaceutical Engineering, Silla University, Busan, 614-735. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576