Bo-Young YOO, Jeongeun PARK, Songhee JEON, Young-Kwon SEO, Hyunjin CHO, Jung-Keug PARK
언어
영어(ENG)
URL
https://www.earticle.net/Article/A174787
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원문정보
초록
영어
Ligament-bone integration was important for ligament tissue reconstruction. Graft integration is required for successful reconstruction of the anterior cruciate ligament. We made a comparative study on the effect of silk scaffold and lyophilized collagen/HA substrate-containing silk scaffold (composite silk scaffold). As this result, proliferation, and bone-related marker expression in vitro were well observed in UC-MSC-seeded composite silk scaffolds compared to the cell-seeded silk scaffold. Further, silk and composite silk scaffolds were implanted into the knees of rabbits as artificial ligament, and they were harvested 24 weeks after implantation for assessing ligament-to-bone integration. It is thought that the lyophilized collagen/HA substrate is highly biocompatible in vitro and enhances wound healing in vivo.
키워드
collagenhyaluronic acidscaffoldUC-MSC
저자
Bo-Young YOO [ Dongguk University of Research Institute of Biotechnology(DURIB), Seoul, Korea,100-723. ]
Jeongeun PARK [ Department of Medical Biotechnology, Dongguk University, Seoul, Korea, 100-715. ]
Songhee JEON [ Dongguk University of Research Institute of Biotechnology (DURIB), Seoul, Korea, 100-273. ]
Young-Kwon SEO [ Dongguk University of Research Institute of Biotechnology (DURIB), Seoul, Korea, 100-273. ]
Hyunjin CHO [ Dongguk University of Research Institute of Biotechnology (DURIB), Seoul, Korea, 100-273. ]
Jung-Keug PARK [ Department of Medical Biotechnology, Dongguk University, Seoul, Korea, 100-715. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동