Microalgae has received attention as an attractive feedstock for renewable biodiesel production due to their desirable characteristics such as rapid growth rate, high lipid contents, and resistance to contamination which can be utilized as microalgal bio-fuel. However, it is indispensable to further develop microalgae strains to display some ideal phenotype for more effective biofuel production. Toward this aim, targeted genetic manipulation was utilized to enhance lipid production in microalgae.When three kinds of microalgae were treated by MAP kinase inhibitor, the lipid content was increased in common. Therefore, MAP kinase affects the lipid biosynthesis in a negative way in microalgae. Based on this fact, repression of MAP kinase genes using RNA interference approach was employed in the model green alga Chlamydomonas reinhardtii. We currently obtain transformants and RT-PCR and phenotype analysis are going to be conducted to investigate the relationship between MAP kinase signaling and lipid biosynthesis. Regulation of MAP kinase genes allows the algal strains to contain high lipid contents for enhanced biofuel production.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
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