Earticle

초록

영어

Jeju island is a rich repository of natural resources escecially marine resources and we research the Jeju marine organisms and algae. We performed screening tests about 100 species marine algae be collected in Jeju island for examination of antioxidant and anti-inflammatory effects. One of them, Dictyopteris undulata, has good antioxidant and anti-inflammatory effects. This study focused on evaluation of the antioxidant and anti-inflammatory activity from D. undulata extracts. D. undulata was extracted using 80% ethanol and then fractionated sequentially with n-hexane, ethyl acetate, and butanol. To screen for antioxidant and anti-inflammatory agents effectively, we first examined the inhibitory effect of the D. undulata extracts on the production of oxidant stresses (DPPH, xanthine oxidase and superoxide). In addition, we examined the inhibitory effects of D. undulata on the production of pro-inflammatory factors (NO, PGE2, TNF-α, IL-6 and IL-β) in murine macrophage cell line RAW 264.7 activated with lipopolysaccharide (LPS). Of the sequential solvent fractions of D. undulata, ethylacetate fractions decreased production of oxidant stresses (DPPH and superoxide). For anti-inflammatory measurement, the ethylacetate fractions of D. undulata inhibited the production of pro- inflammatory factors. These results suggest that D. undulata has significant effects on oxidant stresses and pro-inflammatory factors and is a possible antioxidant and anti-inflammatory therapeutic algae.

키워드

저자

• Yu Mi KANG [ Jeju Biondiversity Reserch Institute, Jeju Technopark. ]
• Won Jong YOON [ Jeju Biondiversity Reserch Institute, Jeju Technopark. ]
• Myoung Suk KO [ Jeju Biondiversity Reserch Institute, Jeju Technopark. ]
• Dong Sam KIM [ Jeju Biondiversity Reserch Institute, Jeju Technopark. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576