Succinic acid was regarded as one of the most important platform chemicals. It can be used as a precursor of numerous products, including pharmaceuticals, feed additives, green solvents, and biodegradable polymers. Nowadays commercially available succinic acid is produced by chemical synthesis. However, attention has been focused on succinic acid produced by microorganisms as an alternative to chemical synthesis. Actinobacillus succinogenes produces a comparatively large amount of succinic acid, and is recognized as one of the most promising microorganisms for industrial succinic acid production. In this study, we carried out fermentation to produce succinic acid from glucose using 1L batch fermentation with different levels of initial concentration of glucose, temperature and pH. The initial glucose concentration and pH could influence cell growth and production of succinic acid. The conditions of optimum temperature and pH were 40℃ and 6.8, respectively. Other carbon sources including fucose, sorbitol, mannitol, sucrose could be utilized as alternatives to glucose. Consequently, this study provides information about physiological and batch cultural features of A. succinogenes .
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동