Coordination between Fe3+ and catechol ligand has been believed to play an important role in raising the hardness and the extensibility of mussel cuticle and contribute to self-healing mechanism of mussel’s tissue. We have reported self-healing protein hydrogel cross-linked by Fe3+-catechol ligand coordination, inspired by maturing mechanism of mussel cuticle. The hydrogel were prepared as the following manner. Recombinant mussel foot protein 1 (mfp1) was dissolved in PBS buffer to 20wt%. Then, FeCl3 was added into the solution to 30mole% against catechol concentration. By adding 1M NaOH, the pH of it was increased by 10. The mechanical properties of the hydrogel had been compared with those of covalently cross-linked hydrogel prepared by I04 - oxidation. Gelation time, dynamic modulus, and relative degree of self-healability of the hydrogels were measured by an Advanced Rheometric Expansion System (ARES).
키워드
hyrogelself-healing materialmussel foot protein
저자
DONG YEOP OH [ POSTECH Ocean Science and Technology Institute (POSTI), Pohang Univerisity of Science and Technology, 790-784 Pohang, South Korea. ]
BUM JIN KIM [ Department of Chemical and Materials Engineering, Pohang Univerisity of Science and Technology, 790-784 Pohang, South Korea. ]
DONG SOO HWANG [ POSTECH Ocean Science and Technology Institute (POSTI), Pohang Univerisity of Science and Technology, 790-784 Pohang, South Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
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