Fermented foods contain various beneficial microorganisms. Lactic acid bacteria (LAB) including Lactobacillus, Bifidobacterium, and Pediococcus are most popular microorganisms in fermented foods. Theses bacteria exist in gastrointestinal (GI) tract and affect digestion system maintaining microorganism balance. In this study, we investigated the effect of LAB culture extracts on the nematode Caenorhabditis elegans focusing on host animals’ digestion system. In order to verify whether the small molecules or metabolites produced by LAB are beneficial for host animals’ digestion system, the extracellular extract was administered into C. elegans together with their food bacteria, E. coli. As a result, extracellular non-protein part of extracts significantly reduced the indigestion of foods in intestine and improved the defecation. Enhanced digestion and defecation increased the body growth of adult animals and improved the survival ratio of middle-aged adults. We have also found that LAB extracts inhibited the growth of E. coli when the extract was added to the culture of E. coli. These results demonstrate that LAB extracts have a great potential as health beneficial supplements by improving digestion and killing harmful bacteria in GI tract.
키워드
Lactic Acid BacteriaDigestionExtractC. elegans
저자
Young Sun YOU [ Dept. of Food and Nutrition, Myongji University, Yongin, Gyeonggi-Do, 449-728 South Korea. ]
Shin Sik CHOI [ Dept. of Food and Nutrition, Myongji University, Yongin, Gyeonggi-Do, 449-728 South Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동