Novel transdermal delivery systems were developed for improving skin penetration of natural substances. Polygonum aviculare L. (P. aviculare) extracts were selected to encapsulate in delivery system because P. aviculare extracts could be applicable to antiaging and whitening agents by in vitro biological activity assay. Liposome and polymeric micelle were developed for improving skin penetration of P.aviculare extracts. The entrapment efficiency of liposome was higher than polymeric micelle. Therefore we investigated further experiment using liposome system. Franz diffusion cell and CLSM studies showed that this system promoting skin penetration of P. aviculare extracts. In vivo studies using guinea pigs and hairless mice indicated liposome system was better than control in their effectiveness on the wrinkle and whitening improvement by promoting skin penetration of P. aviculare extracts.
저자
Soo Nam PARK [ Department of Fine Chemistry, Seoul National University of Science and Technolgy. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동