Earticle

초록

영어

In this talk, I will present the use of physically modified microfluidic channels towards various biomedical applications including single cell analysis and organ chips. The physical modification can be realized either by embedding physical micro/nanostructures or including a topographically patterned substrate at micro- or nanoscale inside a channel. To enable micro/nanofabrication with microfluidics, a simple capillarity-driven lithographic method termed “capillary force lithography” is introduced for fabricating micro/nanostructures onto a surface or inside a microfluidic channel. In the first part, hollow micro-wells are integrated inside a microfluidic channel to capture cells at single cell level. Using this microfluidic platform, we carried out programmable time-course live-cell imaging aided by fluorescent image processing. In the second part, the method is applied for mimicking various aspects of in-vivo environments for cells or tissues. Two organ chips are presented for potential drug screening and advanced tissue engineering applications: heart and kidney chips.

키워드

저자

• Kahp-Yang SUH [ School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 151-742, Korea. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576