Earticle

초록

영어

This study was aimed to examine the prescribing patterns of antivirals in chronic hepatitis B(CHB)for outpatients. National Health Insurance adjudicated claims data(total 1,426,065 claims) dated March 19, 2008 submitted from nationwide healthcare providers to Health Insurance Review and Assessment Service were used in this study. 2,965 claims included CHB diagnosis(ICD-10 code B18.0 and B18.1). 44.2%(1,311) of CHD related claims included antiviral prescription such as lamivudine, clevudine, adefovir and entecavir which were currently available. Lamivudine, adefovir, clevudine and entecavir shared 54.9%, 19.9%, 13.2% and 11.9%, respectively among antiviral prescriptions. Adefovir and entecavir 1mg presumed as the 2nd line therapy for HBV resistant cases were shared 23.3% of overall antiviral prescriptions. There were statistically significant difference in prescription patterns according to age and instititution type: Lamivudine usage was higher in younger(< 20) and older age group(> 70 year old) than others(p = 0.016), and adefovir and entecavir which were relatively newer antivirals had higher prescription rate in higher level of institutions such as the 3rd level hospital than others(p < 0.001). This study would be of help to makeappropriate drug therapy plan for CHB patients.

목차

Abstract
 연구방법
  분석데이터
  분석대상질병
  분석대상약제
  분석방법
 연구결과
  만성 B형간염 외래환자의 특성
  만성 B형간염 외래환자의 항바이러스제 처방 양상
  항바이러스제 처방약 종류에 영향을 미치는 요인
 고찰 및 결론
 참고문헌

키워드

저자

• 공혜경 [ Hye Kyung Kong | 숙명여자대학교 약학대학 ]
• 손현순 [ Hyun Soon Sohn | 숙명여자대학교 약학대학 ]
• 최경업 [ Kyung Eob Choi | 건강보험심사평가원 ]
• 권진원 [ Jin-Won Kwon | 국보건의료연구원 ]
• 신현택 [ Hyun Taek Shin | 숙명여자대학교 약학대학 ] Correspondence

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국임상약학회지 [Korean Journal of Clinical Pharmacy]

• 간기

  계간

• pISSN

  1226-6051

• 수록기간

  1991~2026

• 등재여부

  KCI 등재

• 십진분류

  KDC 518 DDC 615