Earticle

초록

영어

This study was carried out to observe the impacts of a mouse’s inhalation of toxic gas SO2 generated from combustion on its organs by different concentrations. As for research methods: First, after concentrations of SO2 generation from combustion had been set to three: low (10.4 ppm), middle (24.9 ppm) and high (122 ppm) through Gas Toxicity Testing Method (KS F 2271) and SO2 combustion gas was exposed to eight mice in each concentration. Five mice that were able to move based on LD50, a criterion, which sets the down time of a mouse’s average behaviors to over 9 minutes, were randomly selected in each concentration, and they were set up as the subjects of the study on toxicity bio-markers. Second, tissues were taken from heart, liver, lungs, spleen and the thymus gland of the mice selected in each concentration and a pathological examination of them was carried out. As a result, microvascular congestion appeared in the heart, and cell necrosis, cortex congestion and tubule medulla congestion, etc. in each concentration were observed in addition to vascular congestion in liver, lungs, spleen and the thymus gland. Also, it was found that the higher the concentrations of SO2 exposure is, the greater, the changes in the organs get. Through this study, SO2 of various toxic gases generated from fire turned out to affect the tissues of each organ of a mouse, it is expected that the toxic gases may greatly affect human body in case of actual fire, and this study is evaluated as having a significance as a basic data on inhalation toxicity assessment of toxic substances generated in combustion.

목차

Abstract
 1. 서론
 2. 연구 대상 및 방법
  2.1 실험동물 및 사육환경
  2.2 mouse를 이용한 건축물 마감재료 가스유해성시험 (SO2)
  2.3 mouse를 이용한 건축물 마감재료 가스유해성시험(SO2)의 병리독성 실험
 3. 결과
  3.1 건축물 마감재료 가스유해성시험 (SO2)
  3.2 마우스(mouse)를 이용한 건축물 마감재료 가스유해성시험 (SO2)의 신체부위별 병리 독성 결과
 4. 결론 및 제언
 5. 참고문헌

키워드

저자

• 이동호 [ Dong-Ho Rie | 인천대학교 소방방재연구센터 ]
• 조남욱 [ Nam-Wook Cho | 한국건설기술연구원 ]
• 최순영 [ Soon-Young Choi | 인천대학교 소방방재연구센터 ] 교신저자

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  대한안전경영과학회지 [Journal of Korea Safety Management & Science]

• 간기

  계간

• pISSN

  1229-6783

• eISSN

  2288-1484

• 수록기간

  1999~2025

• 십진분류

  KDC 530 DDC 620