It is commonly believed that black soybean (Glycine max: BB) prevents and alleviates hair loss. However, few studies have directly assessed the effect of BB on hair growth. We presently evaluated the mitosis induction on dermal papillae cell and mitogenic effect on NIH3T3 cells in vitro. To elucidate the hair growth promoting effect in vivo, anagen induction and hair restoration were examined in a shaving model of C57BL/6 mice. We also conducted biochemical analysis of blood plasma. Significant stimulation of dermal papillae and NIH3T3 cell proliferation were observed by treatment of BB in a dose-dependent manner. BB markedly promoted hair growth and significantly improved blood total antioxidant capacity and reduced lipid peroxidation and triglyceride level. These results suggest that BB has hair growth promoting effect and it is a potent candidate for the prevention of hair loss.
목차
Abstract 서론 재료 및 방법 시료의 준비 모유두 세포의 증식 활성 모세 혈관 확장 효과 평가 C57BL/6 마우스의 성장기 모낭 유도 평가 통계처리 결과 및 고찰 모유두 세포의 증식 활성 모세 혈관 확장 효과 평가 C57BL/6 마우스의 성장기 모낭 유도 평가 요약 문헌
키워드
black soybeanC57BL/6 micehair growth promotion
저자
전희영 [ Hee Young Jeon | (주)아모레퍼시픽 기술연구원 ]
김승훈 [ Seung Hun Kim | (주)아모레퍼시픽 기술연구원 ]
김채욱 [ Chae Wook Kim | (주)아모레퍼시픽 기술연구원 ]
신현정 [ Hyun Jeong Shin | (주)아모레퍼시픽 기술연구원 ]
서대방 [ Dae Bang Seo | (주)아모레퍼시픽 기술연구원 ]
이상준 [ Sang Jun Lee | (주)아모레퍼시픽 기술연구원 ]
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