Earticle

초록

영어

These studies were conducted to investigate the alcohol degradation effects of the extract of herbal composition (DTS20) containing Viscum album L., Lycium chinense L., Inonotus obliquus and Acanthopanax senticosus H., on the alcohol administered mice. To investigate anti-hangover effect, alcohol and alcohol dehydrogensae (ADH) concentration of blood were measured after oral administration of ethanol. The administration of DTS20 (200-500 mg/kg) had beneficial actions toward alcohol degradation in acute alcohol treated mice model. The oral administration of DTS20 showed decreased gastric mucous membrane damage produced in ethanol treated mice. In addition, intraperitoneal administration of DTS20 showed anti-inflammatory effects in inhibition tests of vascular permeability produced by acetic acid. DTS20 also reduced the concentration of nitric oxide (NO), tumor necrosis factor (TNF)-α in macrophages that were activated by LPS. These results demonstrate that DTS20 possesses potential to stimulate the alcohol degradation and inhibit the inflammatory effects in mice.

목차

Abstract
 1. 서론
 2. 재료 및 방법
  2.1. 실험동물
  2.2. 생약의 종류 및 시료의 추출
  2.3. 알코올 분해능 측정
  2.4. 알코올 섭취에 의한 위출혈 효과
  2.5. 혈중 알코올분해 효소의 함량
  2.6. 모세혈관투과 억제 실험
  2.7. 염증성 성분의 생산 억제에 미치는 효과
  2.8. 통계처리
 3. 결과 및 고찰
  3.1. 혼합 약용식물 추출물의 혈중 알코올 농도에 미치는 효과
  3.2. 혈중 알코올분해 효소의 함량
  3.3. 위 출혈 억제 효과
  3.4. 모세혈관투과도 억제실험
  3.5. 세포독성 및 염증성 물질의 생산 억제 효과
 4. 결론
 References

키워드

저자

• 윤택준 [ Taek Joon Yoon | 유한대학 식품영양과 ]
• 조선영 [ Sun Young Jo | 경기대학교 식품생물공학과 ]
• 이수정 [ Sue Jung Lee | 유한대학 식품영양과 ]
• 김은영 [ Eun Young Kim | 유한대학 식품영양과 ]
• 신광순 [ Kwang-Soon Shin | 경기대학교 식품생물공학과 ]
• 서형주 [ Hyung Joo Suh | 고려대학교 식품영양학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  KSBB Journal

• 간기

  격월간

• pISSN

  1225-7117

• 수록기간

  2009~2013

• 십진분류

  KDC 476 DDC 576