Earticle

초록

영어

Water and ethanol extracts of 16 different Korean traditional oriental prescriptions used widely for prevention of degenerative arthritis were prepared and their total phenolic and total flavonoid contents were quantified. Additionally, antioxidant and anti-inflammatory activities of water, ethanol and enzyme-treated extracts were determined by in vitro assays. Total phenolic and total flavonoid contents of three extracts from the 16 different medicinal prescriptions varied from 10.03-78.03 and 0-16.24 mg/g, respectively. Among the three extracts of 16 different medicinal prescriptions tested, ‘Mahangeuigamtang’ showed the potent full term for DPPH (RC50=71.26, 27.33, 63.00 μg/mL) and full term for ABTS (RC50=21.11, 27.45, 152.11 μg/mL) radical scavenging activities, and its water and ethanol extracts exhibited significant cyclooxygenase-2 (COX-2) inhibitory activity (49.10 and 69.06%, respectively). Ethanol and enzyme-treated extracts of ‘Euieuiintang ’ exerted the strongest COX-2 inhibitory activity (68.23 and 75.05%, respectively). ‘Mahangeuigamtang’ and ‘Euieuiintang’ may be useful as potential therapeutic agents for treatment of degenerative diseases, such as inflammation and aging.

목차

Abstract
 서론
 재료 및 방법
  실험재료
  시약
  복합생약추출물 제조
  총 폴리페놀함량 측정
  총 플라보노이드 함량 측정
  DPPH radical 소거활성 측정
  ABTS radical 소거활성
  COX-2 저해 활성 측정
  통계처리
 결과 및 고찰
  총 폴리페놀 함량
  총 플라보노이드 함량
  DPPH radical 소거활성
  ABTS radical 소거활성
  COX-2의 저해활성
 요약
 감사의 글
 문헌

키워드

저자

• 이성규 [ Sung Gyu Lee | (주)엔유씨전자 바이오연구소 ] Corresponding author
• 이은주 [ Eun-Ju Lee | (주)엔유씨전자 바이오연구소 ]
• 박우동 [ Woo-Dong Park | (주)엔유씨전자 바이오연구소 ]
• 김종부 [ Jong-Boo Kim | 주)엔유씨전자 바이오연구소 ]
• 최상원 [ Sang-Won Choi | 대구가톨릭대학교 식품영양학과 ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국식품과학회지 [Korean Journal of Food Science and Technology]

• 간기

  격월간

• pISSN

  0367-6293

• 수록기간

  1969~2011

• 십진분류

  KDC 574 DDC 664