DNA microarray is a multiplex technology used in molecular biology and biomedicine. It consists of an arrayed series of thousands of microscopic spots of DNA oligonucleotides, called features, of which the result should be analyzed by computational methods. Analyzing microarray data using intelligent computing methods has attracted many researchers in recent years. Several approaches have been proposed, in which machine learning based approaches play an important role for biomedical research such as gene expression interpretation, classification and prediction for cancer diagnosis, etc. In this paper, we present an application of the feedforward neural network (SLFN) trained by the singular value decomposition (SVD) approach for DNA microarray classification. The classifier of the single hidden-layer feedforward neural network (SLFN) has the activation function of the hidden units to be ‘tansig’. Experimental results show that the SVD trained feedforward neural network is simple in both training procedure and network structure; it has low computational complexity and can produce better performance with compact network architecture.
목차
Abstract 1. Introduction 2. Single Layer Feedforward Neural Network Trained by SVD 3. Classification of DNA Microarray for Cancer Diagnosis 4. Conclusion References
키워드
DNA microarrayclassificationfeedforward neural networksingular value decomposition.
저자
Hieu Trung Huynh [ Department of Computer Engineering, Chonnam National university ]
Jung-Ja Kim [ Dicision of Bionics and Bioinformatics, Chonbuk National University ]
Yonggwan Won [ Department of Computer Engineering, Chonnam National university ]
보안공학연구지원센터(IJBSBT) [Science & Engineering Research Support Center, Republic of Korea(IJBSBT)]
설립연도
2006
분야
공학>컴퓨터학
소개
1. 보안공학에 대한 각종 조사 및 연구
2. 보안공학에 대한 응용기술 연구 및 발표
3. 보안공학에 관한 각종 학술 발표회 및 전시회 개최
4. 보안공학 기술의 상호 협조 및 정보교환
5. 보안공학에 관한 표준화 사업 및 규격의 제정
6. 보안공학에 관한 산학연 협동의 증진
7. 국제적 학술 교류 및 기술 협력
8. 보안공학에 관한 논문지 발간
9. 기타 본 회 목적 달성에 필요한 사업
간행물
간행물명
International Journal of Bio-Science and Bio-Technology
간기
격월간
pISSN
2233-7849
수록기간
2009~2016
등재여부
SCOPUS
십진분류
KDC 505DDC 605
이 권호 내 다른 논문 / International Journal of Bio-Science and Bio-Technology vol.1 no.1