Earticle

초록

영어

Alginate has been used as popular biomaterials in the forms of hydergel, microporous beads and fibers for biomedical applications. However, more versatile applications were limited by its fragility in spite of excellent biocompatability. Fiber reinforced composites have often been suggested to improve mechanical characteristics and alginate hydrogel was reported to be successfully reinforced by chitin whisker [1] and alginate fibers [2] to improve their physical properties.In this report, a concentrated calcium salt solubilizing silk fibroin was used for ionotropic curing alginate and for preparing fibroin fibers in the hydrogels. Confocal laser scanning microscope analysis indicated that the FITC stained alginate beads prepared with fibroin solution contained both short fibroin fibers and a network-like fibroin fibers of similar diameters. Methanol treatment inducing β-sheet formation increased the mechanical strength of the fibroin reinforced alginate hydrogels. A versatile method of forming fibroin-fiber networks is under development.

키워드

저자

• Jin Sil LEE [ Dept. of Bioengineering and Technology, Kangwon National University, Chunchon, 200-701. ]
• Joon Ho LEE [ Dept. of Bioengineering and Technology, Kangwon National University, Chunchon, 200-701. ]
• Won HUR [ Dept. of Bioengineering and Technology, Kangwon National University, Chunchon, 200-701. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576