Da Sel KIM, Dong Hyun KIM, Jin Ju NAM, Soon Gi HONG, Na Mi KIM, Chang Seo PARK
언어
영어(ENG)
URL
https://www.earticle.net/Article/A145098
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
We tried to analyze effects of Red Ginseng Oil (RGO) and Fractionated RGO (RGOf) on skin barrier function for both in vitro and in vivo. RGO was prepared by using supercritical extraction of the cake produced after extraction of red ginseng with boiling water. RGOf was prepared by hexane fractionation. The effect of RGO on the recovery of tape stripped skin barrier was measured by TEWL by using hairless mouse. Treatment of 0.1% RGO and RGOf showed the fastest recovery of skin barrier function expressed by TEWL compared to those of vehicle and 1% RGO. Alleviation effect of RGO on inflammation of human skin was also evaluated. RGOf significantly alleviated skin inflammation induced by UVB irradiation. In addition, the pro-inflammatory cytokines TNF- α was inhibited more than 60% in HaCaT keratinocytes by RGOf. And RGO and RGOf stimulated gene of differentiation markers, such as TG-1, Keratin 10 and involucrin. Collectively data shown in this study suggest that RGOf have strong skin protective activities by stimulating the epidermal homeostasis and preventing UVB induced skin inflammation.
키워드
Red ginsengSkin barrierAnti-inflammation
저자
Da Sel KIM [ Dept. of Chemical and Biochemical Engineering, Dongguk University, Seoul, 100-715. ]
Dong Hyun KIM [ Dept. of Chemical and Biochemical Engineering, Dongguk University, Seoul, 100-715. ]
Jin Ju NAM [ Dept. of Chemical and Biochemical Engineering, Dongguk University, Seoul, 100-715. ]
Soon Gi HONG [ Ginseng Research Institute, R&D Headquarters, Korea Ginseng Corp, Daejeon, 305-805. ]
Na Mi KIM [ Ginseng Research Institute, R&D Headquarters, Korea Ginseng Corp, Daejeon, 305-805. ]
Chang Seo PARK [ Dept. of Chemical and Biochemical Engineering, Dongguk University, Seoul, 100-715. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회