Earticle

초록

영어

The objective of this research was to investigate the whitening, anti-wrinkle, and anti-inflammatory effect of Jeju water containing vanadium component. In this study, Jeju water was divided into three groups (S1, S2, S3) according to its vanadium contents, i.e., the concentration of V for S1, S2, S3 were 8.0, 24.0, and 26.0 μg/l, respectively. Mushroom tyrosinase inhibition activity and anti-melanogenesis activity against melanoma cell were examined to explore Jeju water's whitening effects. In this test, Jeju water (S1, S2, S3) exhibited 6~8% inhibition activities on tyrosinase and 5~10% reduction of melanin contents in B16F10 melanoma cells. For the study of Anti-wrinkle effects, only S2 showed 5% inhibition on elastase acitivity. Jeju water (S1, S2, S3) showed 10~20% reduction on the lipopolysaccharide-induced secretion of nitric oxide in RAW264.7 cells, indicating its anti-inflammatory effects. In order to determine whether Jeju water could be safely applied to human skin, its cytotoxic effects were determined by colorimetric MTT assays in human dermal fibroblast. In this test, Jeju water did not show any cytotoxicity. All of these findings demonstrate that Jeju water containing vanadium component has beneficial effects which lead to improve human skin health.

키워드

저자

• Sang Suk KIM [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]
• Jung Eun KIM [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]
• Ha Na KO [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]
• Sang Hee BYEON [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]
• In Jeong YANG [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]
• Kyoung Soo KO [ R&D Center, Jeju Special Self-governing Province Development Co., Jeju 695-961, Korea. ]
• Nam Ho LEE [ Department of Chemistry, Cheju National University, Jeju 690-756, Korea. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576