Earticle

초록

영어

Biological effects of nanomaterials with a focus on toxicity should receive great attention since commercial products as well as medical tools increasingly utilize them. Especially, a fundamental understanding of nanotoxicology is highly desirable both from the material’ stand point as well as from the biological system’ point of view. Nanocrystalline titanium dioxide (nano-TiO2) is an important material used in commerce today : for example, cosmetics of sun-cream to block UV radiation. However, despite its wide array of common applications, its pathogenetic role was always suggested under certain conditions. In this work, the toxicity of TiO2 nanoparicles on human skin- and lung cell was investigated using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay- and confocal microscopy for live &dead of cells. The human skin- and lung-cell were purchase from from Korean Cell Line Bank. We observed that TiO2 nanoparticles impedes the cell growth using MTT, and dead cells increase depending on the concentration of TiO2 nanoparticles using confocal microscopy. Based on the results mentioned above, we discuss the toxicity and the safety of TiO2 nanoparicles for the human cells.

키워드

저자

• Joo-kyung LEE [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
• Ah Young KIM [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
• Hyun Suk JUNG [ School of Advanced Materials Engineering, Kookmin University, Seoul, Korea. ]
• Se-Hoon HAN [ School of Advanced Materials Engineering, Kookmin University, Seoul, Korea. ]
• JunHong MIN [ College of BioNano Technology, Kyungwon University, Seongnam, Korea. ]
• HeaYeon LEE [ ISIR-SANKEN, Osaka University, Osaka, Japan. ]
• BaeHo PARK [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576