Among various elements that influence axonal outgrowth in neural cells in vitro, cell-adhesion is one of the most important factors. To improve cell adhesion and neural differentiation, several experiments have explored the effects of the adhesive surface characters. Polydopamine has the potential to be used as a cell- or tissue-adhesive. Surface modification by polydopamine-coating is extremely useful because it does not require the time consuming synthesis of complex linkers and the process is solvent-free and biocompatible. We hypothesized that polydopamine coated surface would enhance neural cell viability and neural differentiation through improving cell adhesion. To test the hypothesis, cell viability and neural differentiation of pheochromocytoma 12 (PC12) cells cultured on polydopamine-coated glass coverslips were examined. Compared to other conventionally produced cell-adhesion material such as gelatin, Polydopamine showed enhanced cell adhesion, which is important for cell viability, as well as better cell differentiation. Polydopamine could be a suitable cell-adhesion material for cell culture or tissue engineering..
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회