Gyuok LEE, heejin SEOL, Sangoh BAN, juryun NA, myunga JUNG, sunoh KIM, chulyung CHOI, taejong SEOUNG, dongwook LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A144805
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Inflammation is a complex process regulated by a cascade of cytokines, growth factors, nitric oxide (NO) and prostaglandins produced by activated macrophages. Activated macrophages play an important role in inflammatory disease via production of cytokines, tumor necrosis factor-alpha (TNF-α) and other imflammatory medicators such as NO and prostaglandin E2 (PGE2). In this study, we investigated the effect of water extract from Stauntonia hexaphylla (S. hexaphylla) and its various fractions for anti-oxidative activity and anti-imflammatory. The fruit of S. hexaphylla was extracted with water, and the concentrated extract was partitioned with hexane, chloroform (CHCl3), ethylacetate (EtOAc), n-Butanol (n-BuOH) and H2O, successively. All of the extract and fractions on 1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity were strong. Moreover, the inhibitory effect on the productions of NO in LPS-stimulated RAW 264.7 cells was tested to evaluate anti-inflammatory potential. Cell viability, as measured by the MTT assay, showed an increase in RAW 264.7 cells pretreated with S. hexaphylla. These results indicate that S. hexaphylla has protective activities against oxidantive damage induced by free radicals. Also it could be considered as a useful functional material in the prevention of inflammatory.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회