Earticle

초록

영어

Hydroxyapatite (HA) has been extensively used as an implant material because of its similarity with human bone composition and its ability to form a strong bond to the human hard tissue. Silver (Ag) and Ag-containing compounds are highly antimicrobial activity to 16 kinds of bacteria. The antibiotic effect of Ag draws much attention because of the low toxicity of the active Ag ion to human cells. We studied the antimicrobial effects of Ag coated HA nanofibers. Dimethylformamide (DMF) solution having polyacrylonitrile (PAN) and sonicated HA was used for the preparation of nanofibers by electrospinning. Ag coated nanofibers were prepared by two ways. The mixture of Ag, PAN, and HA was electrospinned or nanofibers were soaked into Ag solution. The antimicrobial effects of nanofibers against E coli, K pneumoniae (Gram-negative) and S aureus (Gram-positive) were investigated by paper disc or shaking flask method. Nanofibers containing HA and Ag coated nanofibers exhibited high antibacterial activity against gram-negative and gram-positive both. Our results indicated that HA containing fibers might be a promising antimicrobial biomaterial.

키워드

저자

• Kwang-Hwan JHEE [ Dept. of Applied Chemistry, Kumoh National Institute of Technology, Gumi, 730-701. ]
• Jung-Hyun KIM [ Dept. of Applied Chemistry, Kumoh National Institute of Technology, Gumi, 730-701. ]
• Byung-Gil MIN [ Dept. of Nano-Bio Textile Engineering, Kumoh National Institute of Technology, Gumi, 730-701. ]
• Ju-Yeon KIM [ Dept. of Nano-Bio Textile Engineering, Kumoh National Institute of Technology, Gumi, 730-701. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576