β-Carotene is a red-orange color pigment abundant in many plants and fruits. Non-polar β-carotene is commonly separated from the mixture of carotenoids using an organic compound such as hexane. Carotenoids are known as a strong antioxidant which scavenges reactive oxygen species (ROS) or free radicals. However, the instability of carotenoids is an obstacle in the use of them in a variety of biological systems. Here, we investigated the enhancement of health beneficial effect of β- carotene in the Caenorhabditis elegans animal model using synthesized derivatives of β-carotene with a great stability. When novel β-carotene derivatives were fed into animals together with foods, the life-span was pro-longed in their adulthoods. In addition to the pro-longed lifespan, the locomotion of C. elegans was more activated than that of control worms grown without novel β-carotene in spite of old age. Those anti-aging effects were due to the stable activation of antioxidant effect by novel form of β-carotene. Results imply that the stabilized form of β -carotene has a potential for health aid to suppress aging of animals and human beings.
키워드
beta CaroteneC. elegansantioxidant
저자
Ji Suk YOU [ Dept. Food and Nutrition, Myongji University, Yongin, Gyeonggi, 449-728. ]
Shin Sik CHOI [ Dept. Food and Nutrition, Myongji University, Yongin, Gyeonggi, 449-728. ]
Sang Ho KOO [ Dept. of Chemistry, Myongji University, Yongin, Gyeonggi, 449-728. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회