For sustainable development of current industries, many research groups have made an effort to change the currently available crude oil to the renewable biomass as resources. To overcome the general problems of corn- and sugar-based biomass, non-food biomass such as cellulosic and marine biomass has been concerned as alternative biomass for production of biofuels and biochemicals. Contrary to cellulosic biomass (tree, straw, agricultural residue et al.), marine biomass (red, green, brown algae) does not contain lignin, of which presence raises many problems in bioprocess for biomaterial production. Among marine biomass, red algae are mostly composed of cellulose and galactan. Galactan is a representative polymer consisting of D-galactose and anhydro-galactose. For efficient conversion of red algae to biomaterials, both glucose from cellulose and D-galactose from galactan should be fermented. In this study, a food-grade lactic acid bacterium, Lactobacillus casei was chosen to be metabolically engineered to produce a value-added biochemical of lactic acid and a promising biofuel of bioethanol simultaneously from both glucose and galactose. For simultaneous production of lactic acid and bioethanol, two foreign genes coding for pyruvate decarboxylase and alcohol dehydrogenase were expressed and many genes encoding endogenous lactate dehydrogenase were disrupted in Lactobacillus strains. Batch fermentation and transcriptional analysis were undertaken to investigate the simultaneous production of lactic acid and bioethanol. In this research, it is provided that red algae and lactic acid bacteria have a potential to be used for production of biofuels and biochemcials.
저자
Yong-Cheol PARK [ Department of Advanced Fermentation Fusion Science and Technology, Kookmin University, Seoul 136-702, Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회