Glycation of collagen causes skin yellowing via a spontaneous reaction among protein and sugar in the presence of reactive oxygen. Advenced glycosylation end products(AGEs) are produced by attaching an aldehyde group of glucose to amino group of a collagen molecule. These AGEs are yellowish in color and contribute to the yellow or sallow appearance of skin.(1-4) We know that fruit extracts contain a lot of antioxidant compounds and functional cosmetic raw materials. So we studied the effect of gold kiwifruit as anti aging agent and glycation inhibitor in collagen. We screened for in vitro antioxidant and anti-glycation activity of whole kiwifruit extract, kiwi pulp and rind extract. Rind portion exhibited more effective than pulp and whole kiwi extract in result. Thus it was selected to be further fractionated hexane, chloroform, ethyl acetate and butanol. Among these solvent fractions, kiwi rind extract of ethyl acetate (KRE-E) was observed to be the greatest. Immunofluorescence staining for the presence of AGEs in glycated collagen matrix showed that the glycation inhibitory effect of KRE-E and 5 mM of amnoguanidine were similar. Finally a phenolic compound of KRE-E was identified as quercetin-3-rhamnoside by employing HPLC. Recently using agricultural wastes as low cost source of potential raw material in cosmetics is an active research domain. Because these wastes give adventages of low cost and the possibility to reduce environmental problem caused by waste disposal.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회