Bioethanol from cellulosic biomass has the potential to become an competitive fuel resource, but currently requires many technological improvements to be economically viable. One-pot fermentation of cellulosic biomass into bioethanol through consolidated bioprocessing (CBP) using multi-functional microbes can make a major breakthrough for low cost biomass processing. Unfortunately, however, there are no natural microbes which can do this process effectively. Brewer's yeast Saccharomyces cerevisiae is often chosen as a candidate workhorse for CBP owing to its high productivity of ethanol and resistance to ethanol, even though it has no cellulolytic activity. To develop S. cerevisiae as a CBP yeast, it is essential to make yeast produce sufficient amounts of cellulases required for the complete hydrolysis of cellulosic biomass. Hyper-secretion technology using yeast translational fusion partner (TFP) have been applied to produce several fungal cellulases and hemicellulases. Grams per liter of different cellulases could be secreted into culture supernatant during fed-batch fermentation. Reconstituted cellulase cocktails using cellulases produced separately, showed cellulolytic activities on a filter paper and pretreated biomass. Recombinant yeasts of this study will be useful for the development of a cost-effective CBP system to convert cellulosic biomasses into bioethanol.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
간행물명
한국생물공학회 학술대회
간기
반년간
수록기간
1985~2013
십진분류
KDC 476DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회