In this study, liquid culture of Tricholoma matsutake mycelia was performed via biomass production, and its inhibitory effects on melanin biosynthesis were evaluated. The Tricholoma matsutake mycelia extract inhibited 38.6% of tyrosinase activity at 100 ppm, which is higher than that of extracelluar medium at same dose. In addition, when 100 ppm of Tricholoma matsutake mycelia extract was treated to melan-a cells for 3 days, 19% of melanin production was reduced without cell toxicity. These results suggested that cultured Tricholoma matsutake mycelia might be useful as a skin depigmenting material.
목차
Abstract 서론 재료 및 방법 실험시약 송이균사체 배양 시료추출 세포 배양 세포생존율 측정 멜라닌 생성량 측정 Melan-a 세포로부터 Tyrosinase의 추출 Tyrosinase 활성 억제도 측정 통계분석 결과 및 고찰 추출물제조 Tyrosinase 활성억제효과 Melan-a 세포에서의 멜라닌 생성 억제 효과 요약 문헌
키워드
melaninmyceliaTricholoma matsutaketyrosinase
저자
최상윤 [ Sang Yoon Choi | 한국식품연구원 ]
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