Earticle

초록

영어

This study was performed to investigate the effects of ramie (Boehmeria nivea) leaf powder on improvements in lipid metabolism in serum, liver and adipose tissue, and the anti-obesity effect in rats fed a high fat/high cholesterol diet for 4 weeks to induce a hyperlipidemic and obese model rat. Male Sprague-Dawley rats weighting 210 g were divided into four groups; a normal diet group (N), a high fat/high cholesterol diet group (HFC), a high fat/high cholesterol diet with 5% ramie leaf powder group (HFC-RL), and a high fat/high cholesterol diet with 10% ramie leaf powder group (HFC-RH). The body weight gain increased with a high fat/high cholesterol diet, but gradually decreased in the ramie leaf powder fed groups compared with the HFC group. The liver index in the HFC group was highest among the four groups, although the difference was not significant compared with the ramie leaf powder fed groups. The adipose tissues weight in the HFC group was heavier than that of the N group, whereas those of groups fed ramie leaf powder decreased gradually. Alkaline phosphatase activity was not different between the HFC groups, but serum alkaline aminotransferase and lactate dehydrogenase activities decreased significantly after ramie leaf powder feeding. Levels of serum triglyceride, total cholesterol, LDL-cholesterol, atherogenic index and cardiac risk factors tended to decrease in the ramie leaf powder fed groups compared with the HFC group, whereas serum HDL-cholesterol level decreased in the HFC group and markedly increased in the ramie leaf powder fed groups. Levels of triglyceride and total cholesterol in the liver were significantly lower in the ramie leaf powder fed groups than in the HFC group. Levels of triglyceride and total cholesterol in adipose tissues were also lower in the ramie leaves powder fed groups than in the HFC group. The activities of heparinreleasable lipoprotein lipase (LPL) and total-extractable LPL in adipose tissues increased in the HFC group compared to that of the N group, but those of the ramie leaf powder fed groups decreased significantly. These results suggest that ramie leaf powder may improve lipid metabolism in serum, liver and adipose tissue and potentially reduce lipid storage.

목차

Abstract
 서론
 재료 및 방법
  재료
  실험동물의 사육 및 식이
  실험동물의 처리
  혈청 효소 활성 및 지질 함량 측정
  간과 지방조직 중 중성지방과 총콜레스테롤 함량 측정
  지방조직 중 LPL 활성 측정
  통계처리
 결과 및 고찰
  체중증가량, 식이섭취량 및 식이효율
  간조직 및 지방조직 무게
  혈청 중 AST, ALT, ALP 및 LDH 활성
  혈청 중 중성지방 및 총콜레스테롤 함량
  혈청 중 HDL-콜레스테롤과 LDL-콜레스테롤 함량, 동맥경화지수 및 심혈관위험지수
  간조직과 지방조직 중의 중성지방 및 총콜레스테롤 함량
  지방조직의 LPL 활성
 요약
 문헌

키워드

저자

• 이재준 [ Jae-Joon Lee | 조선대학교 식품영양학과 ]
• 박미란 [ Mi-Ran Park | 조선대학교 식품영양학과 ]
• 김아라 [ Ah-Ra Kim | 조선대학교 식품영양학과 ]
• 이명렬 [ Myung-Yul Lee | 조선대학교 식품영양학과 ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국식품과학회지 [Korean Journal of Food Science and Technology]

• 간기

  격월간

• pISSN

  0367-6293

• 수록기간

  1969~2011

• 십진분류

  KDC 574 DDC 664