Jong Deog KIM, Gyu Seung YANG, Jin Hyuk SHIN, Gu Yong CHA, Hui Jin KIM, Jong Suk KWAK, Jae Ho HWANG, Kyeong Ho HAN, Hyo Jin SEO, Suk Jung OH
언어
영어(ENG)
URL
https://www.earticle.net/Article/A129669
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Cell adhesion is essential for tissue and organ formation, and alive of cell. Cell adhesion is also stimulated by VEGF. Cell adhesion is important factor for cancer and obesity. These two kinds of natural products of Siegesbeckiae Herba and Corni Fructus showed novel anti-cell adhesion. In the anti-cell adhesion experiment, U937 cells to IL-1β-chemical stimulated HUVECs were completely suppressed by 28%, 61%, 70% and 158% at different concentration of S. herba and C. fructus inhibited U937 cell adhesion to 12%, 57%, 115% and 132%, respectively. Also, U937 cell adhesion was inhibited by 372%, 613%, 633% and 720% at different concentration of S. herba and was inhibited by 379%, 504%, 567% and 664% at different concentration of C. fructus when interacting with PMA-chemical stimulated U937 cells to HUVECs. Finally, U937 cell adhesion was inhibited by 93%, 95%, 375% and 436% at different concentration of S. herba and was inhibited by 50%, 112%, 231% and 297% when interacting with chemical stimulated U937 to IL-1B-chemical stimulated HUVECs. These results suggest that S. herba and C. fructus extracts could be anti-angiogenesis substances for anti-obesity.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동