Cancer is one of the prime causes of all human deaths in the world. Although there are many anti-cancer drug including chemotherapy to treat cancer, anti-cancer drugs are known to cause adverse effects such as injury of immune system, which constrains their use in tumor treatment. Therefore, it is necessary to investigate novel anti-tumor drugs with improving immunity without harming the host. Mushrooms have attracted more attention recently in the biochemical and medical areas due to their useful therapeutic effects. Especially, Inonotus obliquus, a traditional medicinal mushroom, has been widely used to promote health and longevity. In this study, we investigated the in vitro and in vivo immunostimulating activities of polysaccharides isolated from fruiting body of Inonotus obliquus (PFIO) on macrophages, T lymphocytes and experimental mouse model. Additionally, the signaling pathway of PFIO-mediated macrophage activation was investigated in RAW264.7 macrophage cell line.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동