Silkworm silk is composed of fibroin and sericin and its hydrolysate has been known to be an excellent skin moisturizer, wrinkle controller, and anti-oxidant. The silk proteins, fibroin and sericin contain rich in glycine and serine among 18 different amino acids. Since glycine and serine are the amino acids that consist of mor than 40% of skin amino acids, the silk hydrolysate has been widely used as raw material for cosmetics and functional food. In this study, silk hydrolysate prepared from silkworm gland in Bombyx mori by treating with hot alkali solution was analyzed and compared with that from silkworm cocoon. Compared to silkworm cocoon hydrolysate, the silkworm grand hydrolysate was 15 times more viscose at neutral pH and showed much better skin affinity. The amino acid composition and heavy metal content showed no significant differnce in both hydrolysates but the molecular weight distribution analyzed by SDS-PAGE demonstrated that the molecular weight of silkworm grand hydrolysate is relatively lower than that of silkworm cocoon hydrolysate, which suggests that silkworm gland is more susceptible to alkali hydroysis. From this comparative analysis, the silkworm grand hydrolysate looks very promising if used as raw material for cosmetics.
키워드
Silkworm GrandSilkworm Grand HydrolysisSilkworm Cocoon
저자
Jung Wook HWANG [ Dept. of Quality Control , CHABIO & DIOSTECH, Daejeon, 305-811. ]
Heui Sam LEE [ National Academy of Agricultural Science, RURAL DEVELOPMENT ADMINISTRATION, Suwon, 441-853. ]
Kyuboem HAN [ President & CTO, CHABIO & DIOSTECH, Daejeon, 305-811. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동