Kyung Yun LEE, Seung Min YOO, Taejoon KANG, Ilsun YOON, Bongsoo KIM, Sang Yup LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A129616
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원문정보
초록
영어
As surface-enhanced Raman scattering (SERS) is a convenient and sensitive method that can detect the analytes even on a single molecule level using a simple nanostructure, it has been employing as an attractive strategy for sensitive DNA sensing. Here, we report the development of a multiplex bacterial DNA detection method employing Au particleon-wire systems as a SERS sensing platform1. The Au NW-on-wire exhibits superb reproducibility, excellent sensitivity, and good time stability. A pattern formed by multiplex Au NW sensors provides positional address and identification for each sensor. By using this system, multiplex target DNAs were detected with a detection limit of 10 pM in a quantitative manner. The target DNAs obtained from reference strains and clinical samples were identified by the particle-on-wire SERS sensor developed in this study successfully, predicting practical values of this sensor in a variety of biosensing application where DNA binding involved. [This research was supported by IT Leading R&D Project from the Ministry of Knowledge Economy through IITA, and World Class University Program of MEST.]
키워드
SERSBio-sensorNano-biotechnology
저자
Kyung Yun LEE [ Dept. of Chemical & Biomolecular Engineering, KAIST, Daejeon 305-701, Republic of Korea. ]
Seung Min YOO [ Dept. of Chemical & Biomolecular Engineering, KAIST, Daejeon 305-701, Republic of Korea. ]
Taejoon KANG [ Dept. of Chemistry, KAIST, Daejeon 305-701, Republic of Korea. ]
Ilsun YOON [ Dept. of Chemistry, KAIST, Daejeon 305-701, Republic of Korea. ]
Bongsoo KIM [ Dept. of Chemistry, KAIST, Daejeon 305-701, Republic of Korea. ]
Sang Yup LEE [ Dept. of Chemical & Biomolecular Engineering, KAIST, Daejeon 305-701, Republic of Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동