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세포치료 및 조직공학

Preparation of Biocompatible Scaffold Beadsfor Cartilage Tissue Engineering

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2010 추계학술대회 및 국제심포지움 (2010.10)바로가기
  • 페이지
    pp.234-234
  • 저자
    Mi-Eun KONG, Sung-Hun CHOI, Su-Jin KIM, Su-Jung KIM, Sun-Mi YOO, Joon-Serk SEO, Kyung-Ho KANG, Eun-Sun KO, Dong-Il KIM
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A129540

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원문정보

초록

영어
PCT15 Tissue engineering and regenerative medicine are new research areas investigating how to repair and regenerate impaired organs and tissues using the natural signaling pathway and components of the organism. In the case of joint cartilage, there are no blood vessels and the damaged tissues are not usually regenerated by themselves. For the treatment of damaged cartilage or initial symptom of osteoarthritis, transplant surgery should be carried out with scaffold beads to support the cells transplanted. In this study, the possibility of a manufactured HA-atelo scaffold bead as a support material for cartilage cell therapy was investigated. We compared the manufactured HA-atelo scaffold beads with two other types of commercial scaffold beads such as Cellgen and Cytodex3. The HA-atelo scaffold beads were manufactured through a five-step process including HA dilution, collagen mixture, bead formation, washing, and bead collection. Isolated chondrocytes are cultured and compared in three types of scaffold beads. Cell proliferation was determined by using MTT assay and secreted glycosaminoglycan (GAG) was analyzed quantitatively by using Blyscan GAG assay kit. In conclusion, the manufactured HA-atelo scaffold beads provided the best results for the cultivation of chondrocytes and they can be used in cartilage tissue engineering effectively.

키워드

scaffold chondrocytes hyaluronic acid cell therapy cartilage tissue engineering

저자

  • Mi-Eun KONG [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Sung-Hun CHOI [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Su-Jin KIM [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Su-Jung KIM [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Sun-Mi YOO [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Joon-Serk SEO [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Kyung-Ho KANG [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Eun-Sun KO [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]
  • Dong-Il KIM [ Dept. of Biological Engineering, Inha University, Incheon, 402-751. ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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    피인용수 : 0(자료제공 : 네이버학술정보)

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