H. SONG, S-.H. LEE, D. K. KIM, J. LEE, M-.H. EOM, S-.J. JEON, J-.H CHO, H. J. LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A129468
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원문정보
초록
영어
With increasing environmental awareness and legislation, GS Caltex Corporation, one of the biggest petroleum and petrochemical companies in Korea, has extended its research to industrial biotechnology. In particular, the company is interested in the fermentative production of C4 alcohols, including n-butanol and 2,3-butanediol, because the both alcohols are industrially important chemicals and also can be used as fuel additives. We recently constructed a number of n-butanol over-producing recombinant Clostridium acetobutylicum strains by metabolic engineering. The heterogeneous expression of adh gene, encoding secondary alcohol dehydrogenase, in C. acetobutylicum successfully converted acetone into isopropanol, which is also well known a fuel additive. More recently, the company has started the research on 2,3-butanediol to be further converted into butadiene. Butadiene is mainly used as a raw material for the synthesis of synthetic rubber for manufacturing automotive tyre. We carried out a series of fermentations to evaluate the economic feasibility of the microbial production of 2,3-butanediol. The experimental results turn out that 2,3-butanediol can be produced at a productivity of more than 3.0 g/L/h with a yield of 0.45 g/g glucose. This work was supported by the Energy Efficiency & Resources of the Korea Institute of Energy Technology Evaluation and Planning(KETEP) grant funded by the Korea government Ministry of Knowledge Economy.
키워드
C4 AlcoholsButanolButanediol
저자
H. SONG [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
S-.H. LEE [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
D. K. KIM [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
J. LEE [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
M-.H. EOM [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
S-.J. JEON [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
J-.H CHO [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
H. J. LEE [ R&D center, GS Caltex Corporation, 104-4 Munji-dong, Yusung-gu, Daejeon 305-380, Republic of Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동