Mushrooms-derived polysaccharides are regarded as one of the well-known functional food and biopharmaceutical materials with a great deal of interest. The polysaccharides are the major component of mushrooms that displays various biological activities such as anti-cancer and immunomodulatory effects. It was assessed whether polysaccharides were able to stimulate the functional activation of macrophages and spleenocyte proliferation. The polysaccharides are able to enhance strongly upregulate the phenotypic functions of macrophages such as phagocytic uptake, release of cytotoxic molecules and cytokine secretion. Also, Polysaccharides are able to cell proliferation and cytokine expression on spleenocytes.In this study, we focus on investigating the potential immunomodulatory effects of mushroom with regard to macrophage activation and splenocyte proliferation.
키워드
immunomodulatorypolysaccharideanti-cancer
저자
Duck-Soo KWON [ Department of Bioengineering and Technology, Kangwon National University, Chuncheon, 200-701, Korea. ]
Eock-Kee HONG [ Department of Bioengineering and Technology, Kangwon National University, Chuncheon, 200-701, Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동